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Indianapolis Colts vs San Francisco 49ers Week 7 Predictions, Picks, Odds, and SNF Preview

Indianapolis Colts vs San Francisco 49ers Week 7 Predictions, Picks, Odds, and SNF Preview

The Indianapolis Colts will head to the West Coast with momentum on their side after crushing the Houston Texans in Week 6. Can they cover the spread against an injury-plagued San Francisco side in this Colts vs 49ers showdown?

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